It is thought that upper dermal mast cells are a part of the pathogenesis of melasma. Pathogenesis describes the manner of the development of a disease. Key treatments for melasma reduce mast cells in the upper layers of the skin (such as tranexamic acid and corticosteroids). Stabilizing mast cells is one possible treatment target for […]
New research on low dose naltrexone for treating a variety of chronic conditions is being published on a monthly basis. Recent research has been done that used low dose naltrexone on patients with fibromyalgia, corneal neuropathic pain, cancer, immunothrombosis in COVID-19, epilepsy, and more. A biopharmaceutical company has released data from their Phase 1 clinical […]
Negatan is a product that is no longer commercially available except through compounding pharmacies. Negatan was the brand name for polyphenol sulfonic acid complex – a medication that is particularly effective for treating oral ulcers. Mouth ulcers, also called canker sores, are a common condition and one that is frequently reported to dentists. There are […]
Transdermal patches allow controlled delivery of medication that is either immediate, administered gradually, or both. There are several reasons why this method of administration may be preferred to an oral form of a drug or a topical cream or gel. Transdermal patches are commercially available in prescription and OTC forms and can also be custom […]
An ingredient that is frequently prescribed by dermatologists but may not be well known by all patients is azelaic acid. There are numerous possible uses in dermatology for azelaic acid including in treatments for acne, rosacea, and melasma. Azelaic acid is a powerful anti-inflammatory and antibacterial that fights acne-causing bacteria, reduces inflammation, and exfoliates the […]
There are many medications that are contraindicated with the use of PDE5 inhibitors. Sildenafil and tadalafil are the most commonly prescribed treatments for ED and they generally should not be combined. One drug that has been studied in combination with PDE5 inhibitors is apomorphine. On its own, apomorphine has been shown to be more effective […]
There are many skin conditions that are difficult to treat. In some cases, treatments are available but they are painful, time consuming, expensive, or some combination of these. Topical immunotherapy is a technique that has been used for decades that has high treatment success rates. Despite the high rates of success, it continues to be […]
Dyclonine oral rinse is a popular topical anesthetic formulation with hygienists in particular. It can prevent a gag reflex in some patients, reduce pain from instrumentation, and provide pain relief before an injection. Dentists and hygienists who try dyclonine rinse with their patients are usually convinced that it should be an essential part of every […]
What is Profound gel and why do so many dentists and hygienists use it on a daily basis? You may be familiar with topical anesthetics available from your dental product supplier like benzocaine gels. Unlike a manufactured anesthetic, Profound is a compounded topical anesthetic that is custom made by a pharmacy for dental offices. It […]
A common formulation that is compounded for dermatology offices is BLT cream. This formulation includes a combination of anesthetic ingredients that work together to numb the skin prior to a cosmetic treatment or skin procedure. Cosmetic treatments are becoming more popular and many patients are looking for the most comfortable experience possible. A topical anesthetic […]
